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Glutamine is the most abundant amino acid in the body, and is utilized for multiple functions, including muscle building, protein synthesis, cellular energy, and neurotransmitter production.
- Street et al. (2011) found that glutamine supplementation improved recovery of strength and reduced muscle soreness in active men after intense exercise.
- Legault et al. (2015) investigated the recovery benefits of glutamine in men and women and confirmed the findings from Street’s lab.
- Sasaki et al. (2013) observed that immune system function – which can be compromised after intense exercise – was improved after glutamine supplementation in elite athletes.
Alanine is another abundant and important amino acid. Not only is it necessary for muscle building and protein synthesis, but it also plays a major role in fuel regulation by helping the liver to adjust glucose and nitrogen. In this way, it protects the muscle from being cannibalized during intense exercise.
A dipeptide of alanine and glutamine, L-Alanyl-L-Glutamine has demonstrated unique properties that can benefit hydration and intestinal health.
- Hoffman et al. (2010) showed that L-alanyl-L-glutamine reduced fatigue and improved reaction time and shooting skill after a 40-minute competitive basketball game.
- Leite et al. (2013) demonstrated that L-alanyl-L-glutamine improved intestinal permeability, which could improve the digestion and absorption of other biomolecules and improve immune health.